2012年6月17日星期日

Treatment in children with nephrotic syndrome, calcium is the key!


Children with nephrotic syndrome, treatment of calcium is the key! "And other issues of concern are the majority of patients, Shijiazhuang kidney disease hospital for brief treatment of calcium of nephrotic syndrome in children is the key!"
Treatment in children with nephrotic syndrome, calcium is the key!
The experts pointed out that children with nephrotic syndrome patients, the treatment of children with renal comprehensive calcium is the key. Children with nephrotic syndrome is easy to calcium deficiency, in general, children with nephrotic syndrome have a lot of proteinuria discharge. Lost a lot of protein, blood easy combination of calcium and albumin excreted in conjunction with proteinuria. Children in strong growth and development stage, the relative increase in demand of the body of calcium, so proteinuria excessive loss of calcium is also more prone to cause the body of calcium deficiency in children. If you do not pay attention to calcium in a timely manner to the children or inadequate intake of calcium-rich food, which ultimately caused the calcium is low, induced hypocalcemia convulsions, tetany.
The age of onset of the nephrotic syndrome is more common in children aged 3 to 6, and boys more than girls, its etiology is unknown, recurrence and persistent, longer duration. Children suffering from nephrotic syndrome in a stable condition of kindergarten, kindergarten children with the care, comprehensive rehabilitation of the young child's.
Treatment in children with nephrotic syndrome, calcium is the key!
Therefore, in the comprehensive treatment of children with nephrotic syndrome at the same time, we should note that supplementary vitamin D and calcium to make up the phenomenon of calcium deficiency, to avoid children with low calcium convulsions, tetany. The parents should give the child to eat calcium-rich food, while the drugs make up with the tonic, you can reduce or even avoid hypocalcemia complications. Nephrotic syndrome, how timely treatment of kidney disease in children during treatment, many of which are applied hormone treatment, whether hormonal or other immunosuppressive agents and cytotoxic drugs for symptoms starting on the damaged kidney did not repair. Therefore, in order and then treatment of nephrotic syndrome can be non-hormonal treatment in the medical profession for effective treatment.
In addition to the treatment of nephrotic syndrome requires long-term use of large doses of adrenal cortical hormone pharmacological studies have shown that hormones have the antibody intestinal absorption of vitamin D and calcium role to make such a lack of calcium in children with more stringent and thus easily lead to the activities of the pediatric osteoporosis fracture, treatment of children with nephrotic syndrome should be noted that supplementary vitamin D and calcium to make up for calcium deficiency phenomenon to avoid children with low calcium convulsions, foot twitching, osteoporosis and fractures to the doctor and patient treatment in children with nephrotic syndrome should be noted that the parents give the child to eat calcium foods drugs make up with the tonic you can reduce or even avoid hypocalcemia complications.
If you have children with nephrotic syndrome, treatment of calcium is the key! "Do not quite understand, you can continue to read the following related content.
Nephrotic syndrome diagnosis?

Diagnosis of nephrotic syndrome is obvious to the face, lower limbs, scrotum, often ascites, general systemic conditions, no high blood pressure.
(2) oliguria, urine protein ~, quantitative> 0.1g / (kg · d). Urinary microscopy occasionally a small amount of red blood cells.
(3) lower than normal concentrations of total protein, albumin decreased more significantly (<30g / L), serum protein electrophoresis showed albumin reduce the proportion of globulin increased the proportion of r globulin decreased. Blood cholesterol was significantly higher (> 5. 7mmol / L), normal serum complement.
(4) renal function is normal, and edema was significantly oliguria, transient mild azotemia.
2 nephritis, nephrotic syndrome
The age of onset of school age, clinical features are as follows:
(1) blood pressure can be increased to varying degrees, often paroxysmal or persistent hypertension and hematuria.
(2) of serum complement can be reduced, may have varying degrees of azotemia.
(3) age of onset is more common in children over the age of seven, the edema is usually not serious.
Within three months of the disease, congenital nephrotic syndrome, a rare, mostly autosomal recessive disease, more common in the neonatal period and hygiene performance and simple nephrotic similar.
Nephrotic syndrome should be done to check:
(A) selectivity of proteinuria and urine C3FDP determination: Ⅰ type of selective protein pee C3 and FDP value of the normal type Ⅱ non-selective protein pee C3 and FDP values ​​often more than normal.
(B) urine: In addition to the large number of proteins in the urine can be transparent tube or granular casts sometimes may have a fat pipe type Ⅱ: centrifuged urine red blood cells <10 / HP; II type 10 / HP.
(C) erythrocyte sedimentation rate of growth: often 40-80mm / h, erythrocyte sedimentation rate growth and edema parallel.
(D) biochemical tests: In addition to the total plasma protein reduce the outside white / ball can be inverted to increased blood cholesterol, type Ⅰ type Ⅱ from time increased.
(E) Renal function tests: normal type Ⅰ Ⅱ type have varying degrees of abnormalities.
(F) protein electrophoresis: α2 or β can be significantly increased in the majority of the α1γ globulin lower.
(G) of renal biopsy: ultrastructure and immunopathology observed in order to provide the histomorphological basis.
5 Complications
(1) electrolyte imbalance: hyponatremia, hypokalemia, hypocalcemia.
Thrombosis (2): move the common venous thrombosis of renal vein thrombosis, clinical waist and abdominal pain, hematuria.
(3) infection: upper respiratory tract infections, skin infections, peritonitis.

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