Case of Childhood Nephrotic Syndrome

atient: Zhang Yue, Girl, Three and ten months, Mi Yun County, Beijing.

Treatment history:

On the the middle ten days of August, 2007, the baby suddenly appeared edema in the eyelids without any reasons. For the baby didn’t have any other symptoms, so the parents just ignored it. And a few days later, the edema just faded away by itself.

At the beginning of September, 2007, the baby had obvious edema in the eyelids, faces and the lower limbs. So her parents took her to hospital to have an examination. Urinalysis showed her urine protein is ++++. Biochemistry showed hypoproteinemia, and hyperlipemia. Chest radiograph showed pleural effusion. And the baby also had a cough.

Diagnosis: Primary Nephrotic Syndrome, Myocardial damage and Pneumonia.

She was given some symptomatic treatment and oral hormone. Ten days later, edema and pathological changes of the lungs faded away. And the urine protein became negative when she discharged from the hospital.

11 October, 2010, the reexamination in the Children's Hospital showed the urine protein was +. And according to the doctor, she reduced the intake of the hormone.

30 October, 2010, urine protein was +++, and edema recurred.

31 October, 2010, the parents took Zhang Yue to Shijiazhuang Kidney Disease Hospital to have a further treatment.

The records in Shijiazhuang Kidney Disease Hospital:

Admission complaints: Recurring edema in the eyelids and the body, Urine protein for two months, and a relapse of the disease.

Admission date: October， 2007 ---5 December, 2007

The physical sign and condition when admission: moon-shaped face, slight edema in the eyelids, pitting edema in the lower limbs, obvious distention of the belly, the urine protein+++, occult blood+/—, Urine Protein Quantitation in 24 hours 4.6g/24h, hypoproteinemia, hyperlipemia, high coagulation and viscosity of the blood, and white blood cell increasing.

Diagnosis in Shijiazhuang Kidney Disease Hospital: Primary Nephrotic Syndrome in the stage of inflammatory reaction of the Renal fibrosis.

Treatment: when she was admitted into Shijiazhuang Kidney Disease Hospital, she was given Micro-Chinese Medicine Osmotherapy and western medicines for 35 days to achieve the purpose of dilatation, diuresis, apocatastasis, anticoagulation and antithrombus. On the fifth day, the baby got better with the fading edema. When she was discharged from the hospital, her edema completely disappeared. Mental state was good. Urine Protein Quantitation in 24 hours was 0.3g/24h，total protein was 37.32g/l. White blood cells was 32.34g/l. Hypoproteinemia, hyperlipemia, high coagulation and viscosity of the blood were all got different improvement.

Expert comments: Nephrotic Syndrome is a most seen Childhood Nephropathy. For the treatment, the western medicines often use hormones. The advantage is they can eliminate the large amount of urine protein and edema. The disadvantage is the disease is easy to recur and some side effects may happen. Just like this case, the effect is very good and also quick when the baby girl uses western medicines, but in two months the disease recurs for several times. Every recurrence will accelerate the disease condition and bring difficulty for the following treatment.

This patient was in the inflammatory reaction stage of the kidney fibrosis, in which stage Micro-Chinese Medicine can exert great function. The Micro-Chinese Medicine can control the proceeding of the pathological damages, fibrosis process and the scarring rate of progress. Starting from the disease root, the medicines can repair the damaged kidney functions, gradually improve the kidney functions and effectively eliminate the symptoms of urine protein and edema. The advantages of the Micro-Chinese Medicine Osmotherapy are: for one hand, the medicines are applied to the patients by Osmotherapy, which is by the way of external application, not for oral use, so there will not appear the situation that the children refuse to take medicines and also it can avoid some side effects. For the other hand, it starts from the disease root, and gradually repair the damaged kidney units, so the disease is not easy to recur.