Childhood Nephrotic Syndrome(Childhood NS) is a common disease with a long course. It is a group of clinical syndrome caused by various causes which will lead to renal fibrosis, and during the course of renal fibrosis, the increase of glomerular capillary permeability leads to the formation of large amounts of proteinuria. The main manifestations of this disease are large amounts of proteinuria, hypoproteinemia, hyperlipoidemia and edema at different degrees. The edema of Childhood NS presents as pitting edema over the legs.
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